Example Project 1 – Asthma

Project Goals:

  1. Utilize online databases and computational/biostatistical methods, including PCA, to analyze single-cell RNA sequencing datasets and identify significantly overexpressed and underexpressed genes in asthma shocks.
  2. Explore the individual functions of these genes or their interactions in causing asthma shocks
  3. Outline experimental designs, such as gene knockdowns, to demonstrate the validity and effectiveness of their findings if possible. 

Deliverables:

  1. A research paper exploring the functions of the overexpressed and underexpressed genes in asthma shocks, including code demos.
  2. Expected experimental results demonstrating the validity and effectiveness of the team’s findings, if available.

Timeline:

  • Week 6-7: Conduct literature review on gene expressions associated with asthma shock and find online databases
  • Weeks 8-9: Identification of significantly overexpressed and underexpressed genes, and research on their individual functions or interactions.
  • Final day: Completion of the research paper, including code demos, and potential experimental designs and results if applicable.